Search on: APO B 
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Descriptor English:   Apolipoproteins B 
Descriptor Spanish:   Apolipoproteínas B 
Descriptor Portuguese:   Apolipoproteínas B 
Synonyms English:   Apo B
ApoB
Apoprotein (B)
Apoproteins B
Apo-B  
Tree Number:   D10.532.091.300
D12.776.070.400.300
D12.776.521.120.300
Definition English:   Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA. 
See Related English:   Abetalipoproteinemia
 
History Note English:   85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   1061 
Unique Identifier:   D001055 

Occurrence in VHL:
 

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